Director, Global Compound Management (GCM)

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Job Description

OBJECTIVES/PURPOSE

Organizational leader with responsibilities and strategic influence across multiple functions and/or external collaborations

• Responsible for managing and overseeing compound management scientists and operations at Takeda research sites in Boston, Shonan Japan and drives strategic planning for Compound Management growth, operational excellence and best-practices and ensure compliance with regulatory agencies and organizational laws and regulations.
• In collaboration with key stakeholders, drives effective strategic planning for chemical library expansion optimization, management and improvements in compound management related software solutions.
• Directs the planning, design, sourcing, development, implementation, and maintenance of high-throughput laboratory workflows, automation systems and technical infrastructure including robotic equipment, instruments, software, and databases.
• Directs the functional operations supporting small molecule and biologics sample management and high-throughput deployment of assay-ready plates for high- and medium-throughput screening.
• Leverage GCM’s experience in research lab automation, operations and processing across all of Takeda Research.
• Advances GCM department to proactively identify and meet the evolving needs of global Takeda Research, such as the broadening scope of diverse large molecule sample management, as well as other opportunities.

ACCOUNTABILITIES

• Ensures continuous operation and maintenance of high-throughput laboratory workflows, automation systems and technical infrastructure.
• Manages all aspects of small molecule compound management including additions to library, archiving and deployment of sample plates supporting screening assays internally/externally.
• Develops and implements long term maintenance and replacement strategies for department capital systems, driven by performance monitoring, capacity utilization, leveraging awareness of new technologies.
• Develops and ensures long-term alliances between GCM and Global IT department so as to leverage Systems Engineering’s experience in research lab automation, workflows, operations, integration, and processing across all of Takeda Research.
• Optimizes outsourcing model building robust global logistical frameworks for physical sample shipment including import and export.
• Works to identify and act on opportunities to advance GCM to meet the evolving needs of global Takeda Research, such as the broadening scope of diverse large molecule sample management, as well as other opportunities.
• Accountable for the development of organizational culture and capabilities.

DIMENSIONS AND ASPECTS

Technical/Functional (Line) Expertise

• Outstanding expertise and depth of knowledge within compound management.
• Keeps up with the up-to-date scientific advancement (e.g. competitive landscape, new technology, new research portfolio, and new partnership).
• Expertise with all aspects of designing, integrating, deploying, and maintaining data-driven high-availability high-throughput laboratory automation systems.
• Expertise managing the full life cycle of capital projects from conceptualization, process development and workflow design, budgetary development, budgetary approval, supplier management, requirements and system documentation to on-time/on-budget execution and reporting.
• Expertise with software/database/equipment technical infrastructure and integration, including data modelling, software development/testing/maintenance/configuration management/deployment (preferably C#, VB.NET and .NET framework), database development/maintenance (preferably Oracle and PL/SQL schemas/tables/views/packages/functions/procedures/triggers), robotic and liquid handling equipment protocol development.
• Expertise with monitoring/reporting equipment performance and capacity utilization metrics, liquid handling quality control methods.

Leadership

• Has significant organizational leadership responsibility, including primary responsibility for Global Compound Management and as a member of the Hit Generation and In Vitro Pharmacology team.
• Expertise managing a multi-disciplinary team supporting all aspects of high-throughput laboratory workflows, automation systems and technical infrastructure to ensure operational excellence.
• Experience cultivating and developing relationships geographic and functional responsibilities to leverage opportunities to advance GCM to meet the evolving needs of global Takeda Research.

Decision-making and Autonomy

• Independently manages workload and expectations.
• Scientifically independent.
• Scientific driver for research strategy that impacts group internally and outside area of function.

Interaction

• Initiates and leads external interactions and collaborations with key suppliers and contract research organizations.
• Frequent contact with internal and external personnel at various management levels.
• Builds alliances with local Facilities, EHS, IT, Structural Biology and Biophysics departments, as well as Drug Discovery Units across therapeutic areas.
• Builds alliances between GCM and Global IT department so as to leverage GCM’s experience in research lab automation, operations and processing across all of Takeda Research.

Innovation

• Determines methods on new assignments; makes strategic recommendations on projects.

EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS

• Desirable - PhD degree in a scientific discipline with 12+ years experience, or
• MS with 16+ years experience, or
• BS with 18+ years experience.
• 7 years of Industry experience required.
• 7 years of managerial experience required.
• Good communication skill to establish good relationship with global members.

For Location:

Boston, MA

U.S. Base Salary Range:

$169,400.00 - $266,200.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes